Differential Diagnosis: Bipolar disorder “There are a variety of illnesses that are similar to bipolar disorder, but with less severe upswings,” says NIMH’s Dr. Francis J. McMahon. 362(9386):758. . Differential diagnosis of major depression and bipolar disorder. Clinical characteristics indicative of bipolar disorder versus major depressive disorder identified in this review are based on group differences and may not apply to each individual patient. Clipboard, Search History, and several other advanced features are temporarily unavailable. Kraepelin E. … NIH Differential diagnosis of major depression and bipolar disorder. 2005 Apr;85(3):245-58. doi: 10.1016/j.jad.2004.12.004. Definitional contextualization and epidemiological profiles: The term “depression” is often used, improperly, to refer to any of the various depressive disorders, categorized on a nosographic basis by the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition - (DSM-V) [1]. The estimated lifetime prevalence of major depressive disorder (i.e., unipolar depression) is over 3 and one-half times that of bipolar spectrum disorders. Other conditions to be considered include the following: Epilepsy Like Methods: Challenges in the differential diagnosis of bipolar disorder and major depressive disorder are reviewed, and the clinical utility of several screening instruments is evaluated. Therefore, it is not surprising that without proper screening and comprehensive evaluation many patients with bipolar disorder may be misdiagnosed with major depressive disorder (unipolar depression). CNS Spectr. The clinical presentation of a major depressive episode in a bipolar disorder patient does not differ substantially from that of a patient with major depressive disorder (unipolar depression). RESULTS: The estimated lifetime prevalence of major depressive disorder (i.e., unipolar depression) is over 3 and one-half times that of bipolar spectrum disorders. Depressive symptoms are present in the depressive mood state of bipolar disorder (BPD) and major depression disorder (MDD). Bipolar disorder versus Depression comparison chart; Bipolar disorder Depression; Introduction: Bipolar disorder is a mental illness characterized by episodes of an elevated or agitated mood known as mania, alternating with episodes of depression. Central nervous system diseases (eg, Parkinson disease, dementia, multiple sclerosis, neoplastic lesions) 2. When I think of schizoaffective disorder (D/O), I think of two D/Os combined into one-schizophrenia and a major mood D/O (the mood D/O can either major depression or bipolar D/O). Depression and bi polar disease are considered as psychiartric disorders. Psychopathological characteristics of bipolar and unipolar depression - potential indicators of bipolarity. major depression and mania. Borderline personality disorder. Drug-related conditions (eg, cocaine abuse, side effects of some CNS depressants) 4. The differential diagnosis of depression includes: Grief reaction — depressive symptoms may be transiently present in normal grief.Uncomplicated bereavement and major depression share many symptoms, but active suicidal thoughts, psychotic symptoms, and … Bipolar disorder or manic depressive disorder is a form of a mood disorder that is often confused with having only depression. Major depressive disorder has significant potential morbidity and mortality, contributing to suicide (see the image below), incidence and adverse outcomes of medical illness, disruption in interpersonal relationships, substance abuse, and lost work time. Therefore, it is not surprising that without proper screening and comprehensive evaluation many patients with bipolar disorder may be misdiagnosed with major depressive disorder (unipolar depression). Depression, one of the most commonly diagnosed psychiatric disorders, is being diagnosed in increasing numbers in various segments of the population worldwide. The differential diagnosis for depression includes a wide variety of medical disorders, such as the following: 1. Challenges in the differential diagnosis of bipolar disorder and major depressive disorder are reviewed, and the clinical utility of several screening instruments is evaluated. Differential Diagnosis. In general, antidepressants have demonstrated little or no efficacy for depressive episodes associated with bipolar disorder, and treatment guidelines recommend using antidepressants only as an adjunct to mood stabilizers for patients with bipolar disorder. Differential diagnosis of bipolar disorder and major depressive disorder, https://doi.org/10.1016/S0165-0327(14)70004-7. Because of the symptoms shared between ADHD and bipolar disorder, attaining a differential diagnosis can be complicated. Bipolar disorders are characterized by alternating episodes of mania or hypomania and depression, or mixtures of manic and depressive features. 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